The geometry of DNA supercoils modulates the DNA cleavage activity of human topoisomerase I.

Gentry AC, Juul S, Veigaard C, Knudsen BR, Osheroff N
Nucleic Acids Res. 2011 39 (3): 1014-22

PMID: 20855291 · PMCID: PMC3035449 · DOI:10.1093/nar/gkq822

MeSH Terms (8)

Antineoplastic Agents Cell Line, Tumor DNA, Superhelical DNA Cleavage DNA Topoisomerases, Type I Humans Intercalating Agents Topoisomerase I Inhibitors

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