Molecular correlates of spontaneous activity in non-human primates.

Mitchell AC, Aldridge G, Kohler S, Stanton G, Sullivan E, Garbett K, Faludi G, Mirnics K, Cameron JL, Greenough W
J Neural Transm (Vienna). 2010 117 (12): 1353-8

PMID: 20838826 · PMCID: PMC3649869 · DOI:10.1007/s00702-010-0483-7

In our monkey model, cortical ARC and BDNF expressions were strongly correlated with spontaneous physical activity. The expressions of ARC and BDNF were inversely correlated with serum CRP levels, suggesting that CRP could be a putative peripheral marker of brain resiliency.

MeSH Terms (11)

Animals Brain-Derived Neurotrophic Factor C-Reactive Protein Cytoskeletal Proteins Female Macaca mulatta Models, Animal Motor Activity Motor Cortex Nerve Tissue Proteins Physical Conditioning, Animal

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