Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.

Moslehi J, Minamishima YA, Shi J, Neuberg D, Charytan DM, Padera RF, Signoretti S, Liao R, Kaelin WG
Circulation. 2010 122 (10): 1004-16

PMID: 20733101 · PMCID: PMC2971656 · DOI:10.1161/CIRCULATIONAHA.109.922427

MeSH Terms (17)

Animals Basic Helix-Loop-Helix Transcription Factors Cardiomyopathy, Dilated Cell Hypoxia Heart Failure Hypoxia-Inducible Factor-Proline Dioxygenases Hypoxia-Inducible Factor 1, alpha Subunit Mice Mice, Inbred C57BL Mice, Mutant Strains Mitochondria Myocardial Stunning Myocardium Myocytes, Cardiac Neovascularization, Physiologic Phenotype Procollagen-Proline Dioxygenase

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