Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling.

Dikalova AE, Góngora MC, Harrison DG, Lambeth JD, Dikalov S, Griendling KK
Am J Physiol Heart Circ Physiol. 2010 299 (3): H673-9

PMID: 20639222 · PMCID: PMC2944492 · DOI:10.1152/ajpheart.00242.2010

MeSH Terms (19)

Analysis of Variance Angiotensin II Animals Blood Pressure Blotting, Western Endothelium, Vascular Hydrogen Peroxide Hypertension Mice Mice, Transgenic Muscle, Smooth, Vascular NADH, NADPH Oxidoreductases NADPH Oxidase 1 NG-Nitroarginine Methyl Ester Nitric Oxide Nitric Oxide Synthase Type III Polymerase Chain Reaction Up-Regulation Vasodilation

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