A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.

Cheng Q, Tucker EI, Pine MS, Sisler I, Matafonov A, Sun MF, White-Adams TC, Smith SA, Hanson SR, McCarty OJ, Renné T, Gruber A, Gailani D
Blood. 2010 116 (19): 3981-9

PMID: 20634381 · PMCID: PMC2981546 · DOI:10.1182/blood-2010-02-270918

MeSH Terms (23)

Animals Antibodies, Monoclonal Anticoagulants Carotid Artery Thrombosis Cats Disease Models, Animal Dogs Factor XI Factor XI Deficiency Factor XIIa Factor XII Deficiency Humans In Vitro Techniques Male Mice Mice, Inbred BALB C Mice, Knockout Papio anubis Partial Thromboplastin Time Pulmonary Embolism Rabbits Species Specificity Thrombosis

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