Haplotype analysis discriminates genetic risk for DR3-associated endocrine autoimmunity and helps define extreme risk for Addison's disease.

Baker PR, Baschal EE, Fain PR, Triolo TM, Nanduri P, Siebert JC, Armstrong TK, Babu SR, Rewers MJ, Gottlieb PA, Barker JM, Eisenbarth GS
J Clin Endocrinol Metab. 2010 95 (10): E263-70

PMID: 20631027 · PMCID: PMC3050098 · DOI:10.1210/jc.2010-0508

MeSH Terms (18)

Addison Disease Adult Autoimmune Diseases Autoimmunity DNA Mutational Analysis Endocrine Cells Female Gene Frequency Genetic Predisposition to Disease Haplotypes HLA-B8 Antigen HLA-DR3 Antigen Humans Linkage Disequilibrium Male Pedigree Polymorphism, Single Nucleotide Risk

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