Assessment of feeding behavior in laboratory mice.

Ellacott KL, Morton GJ, Woods SC, Tso P, Schwartz MW
Cell Metab. 2010 12 (1): 10-7

PMID: 20620991 · PMCID: PMC2916675 · DOI:10.1016/j.cmet.2010.06.001

The global obesity epidemic has heightened the need for an improved understanding of how body weight is controlled, and research using mouse models is critical to this effort. In this perspective, we provide a conceptual framework for investigation of feeding behavior in this species, with an emphasis on factors that influence study design, data interpretation, and relevance to feeding behavior in humans. Although we focus on the mouse, the principles presented can be applied to most other animal models. This document represents the current consensus view of investigators from the National Institutes of Health (NIH)-funded Mouse Metabolic Phenotyping Centers (MMPCs).

Copyright 2010 Elsevier Inc. All rights reserved.

MeSH Terms (14)

Age Factors Animals Disease Models, Animal Eating Feeding Behavior Female Habituation, Psychophysiologic Male Mice Mice, Inbred C57BL Obesity Sex Factors Stress, Psychological Weight Gain

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