Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage.

Huang H, Kozekov ID, Kozekova A, Rizzo CJ, McCullough AK, Lloyd RS, Stone MP
Biochemistry. 2010 49 (29): 6155-64

PMID: 20604523 · PMCID: PMC2907095 · DOI:10.1021/bi100364f

MeSH Terms (11)

Acrolein Amines Cyclopropanes Deoxyguanosine DNA Adducts DNA Damage DNA Repair Models, Molecular Nucleic Acid Conformation Oligodeoxyribonucleotides Oligopeptides

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