Blood pressure control in chronic kidney disease: is less really more?

Lewis JB
J Am Soc Nephrol. 2010 21 (7): 1086-92

PMID: 20576804 · DOI:10.1681/ASN.2010030236

BP control is critical in the treatment of patients with chronic kidney disease. Recent guidelines now recommend a BP goal of <130/80 mmHg. Clinical trials using a randomized, intention-to-treat design have not established the benefits of this goal; rather, observational data and secondary or subgroup analyses drove the development of the new guidelines. A variety of observations suggest potential adverse events associate with achieving too low a BP in patients with chronic kidney disease, and ongoing randomized trials will have to establish the benefits or risks of meeting this goal.

MeSH Terms (7)

Antihypertensive Agents Blood Pressure Chronic Disease Humans Hypertension Kidney Diseases Practice Guidelines as Topic

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