Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV.

Hicar MD, Chen X, Briney B, Hammonds J, Wang JJ, Kalams S, Spearman PW, Crowe JE
J Acquir Immune Defic Syndr. 2010 54 (3): 223-35

PMID: 20531016 · PMCID: PMC2930513 · DOI:10.1097/QAI.0b013e3181dc98a3

MeSH Terms (18)

AIDS Vaccines Amino Acid Sequence Antibodies, Monoclonal Antibody Specificity Antigens, CD19 B-Lymphocytes Cells, Cultured env Gene Products, Human Immunodeficiency Virus gag Gene Products, Human Immunodeficiency Virus Gene Expression Regulation Green Fluorescent Proteins HIV Humans Hybridomas Immunoglobulins Molecular Sequence Data Protein Multimerization Virion

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