Conditional ablation of Ikkb inhibits melanoma tumor development in mice.

Yang J, Splittgerber R, Yull FE, Kantrow S, Ayers GD, Karin M, Richmond A
J Clin Invest. 2010 120 (7): 2563-74

PMID: 20530876 · PMCID: PMC2898608 · DOI:10.1172/JCI42358

MeSH Terms (21)

Animals Apoptosis Aurora Kinase A Aurora Kinase B Aurora Kinases Cyclin-Dependent Kinase 2 Cyclin-Dependent Kinase 4 Genes, ras I-kappa B Kinase Melanocytes Melanoma Mice Mice, Knockout Mice, Transgenic Neoplasms NF-kappa B Phosphorylation Protein-Serine-Threonine Kinases Transcription, Genetic Transcription Factor RelA Tumor Suppressor Protein p53

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