Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development.

Pitts TM, Tan AC, Kulikowski GN, Tentler JJ, Brown AM, Flanigan SA, Leong S, Coldren CD, Hirsch FR, Varella-Garcia M, Korch C, Eckhardt SG
Clin Cancer Res. 2010 16 (12): 3193-204

PMID: 20530704 · PMCID: PMC2889230 · DOI:10.1158/1078-0432.CCR-09-3191

MeSH Terms (23)

Animals Biomarkers, Tumor Cell Line, Tumor Drug Delivery Systems Drug Resistance, Neoplasm Drug Screening Assays, Antitumor Feasibility Studies Female Gene Dosage Gene Expression Profiling Gene Knockdown Techniques Genes, ras Humans Imidazoles Mice Mice, Nude Mutation Protein Kinase Inhibitors Proto-Oncogene Proteins B-raf Pyrazines Receptor, IGF Type 1 Reproducibility of Results Xenograft Model Antitumor Assays

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