Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress.

Bansal S, Liu CP, Sepuri NB, Anandatheerthavarada HK, Selvaraj V, Hoek J, Milne GL, Guengerich FP, Avadhani NG
J Biol Chem. 2010 285 (32): 24609-19

PMID: 20529841 · PMCID: PMC2915697 · DOI:10.1074/jbc.M110.121822

MeSH Terms (15)

Animals Chlorocebus aethiops COS Cells Cytochrome P-450 CYP2E1 DNA, Mitochondrial Endoplasmic Reticulum Ethanol Glutathione Humans Mitochondria Mitochondria, Liver Oxidative Stress Rats Rats, Sprague-Dawley Subcellular Fractions

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