Cognitive profile of children with neurofibromatosis and reading disabilities.

Cutting LE, Levine TM
Child Neuropsychol. 2010 16 (5): 417-32

PMID: 20521183 · PMCID: PMC2929318 · DOI:10.1080/09297041003761985

A large percentage of children with Neurofibromatosis Type 1(NF-1) have learning disabilities, often in the realm of reading. Previous studies have indicated that children with NF-1 show a neuropsychological profile similar to idiopathic reading disabilities (IRD); however, studies typically have not subdivided children with NF-1 into those who do and do not have RD (NF+RD and NFnoRD, respectively). The current study examined the cognitive profile of children with NF-1 with and without RD and compared them to children with IRD as well as to typically developing readers (Controls). Findings showed that children with NF+RD performed similarly to children with IRD on phonological, rapid naming, and reading comprehension measures; however, children with NF+RD displayed pronounced visual-spatial deficits as compared to IRD and Control groups. In addition, when comparing the NF-1 groups to each other as well as to the control and IRD groups, the current study reported that there were no oral language differences; lack of findings in the realm of oral language was attributed to the fact that groups were equated on IQ. Overall, findings suggest that a more refined classification of children with NF-1 may be helpful for tailoring academic interventions.

MeSH Terms (13)

Adolescent Attention Deficit Disorder with Hyperactivity Child Cognition Diagnostic and Statistical Manual of Mental Disorders Dyslexia Female Humans Learning Disorders Male Neurofibromatosis 1 Neuropsychological Tests Wechsler Scales

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