Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.

Albaugh VL, Vary TC, Ilkayeva O, Wenner BR, Maresca KP, Joyal JL, Breazeale S, Elich TD, Lang CH, Lynch CJ
Schizophr Bull. 2012 38 (1): 153-66

PMID: 20494946 · PMCID: PMC3245588 · DOI:10.1093/schbul/sbq053

MeSH Terms (21)

Animals Antipsychotic Agents Benzodiazepines Carnitine Clozapine Energy Metabolism Fatty Acids, Nonesterified Female Haloperidol Insulin Resistance Lipolysis Male Malonyl Coenzyme A Mice Olanzapine Piperazines Rats Rats, Sprague-Dawley Risperidone Thiazoles Vitamin B Complex

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