Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate.

Chowdhury G, Murayama N, Okada Y, Uno Y, Shimizu M, Shibata N, Guengerich FP, Yamazaki H
Chem Res Toxicol. 2010 23 (6): 1018-24

PMID: 20443640 · PMCID: PMC3843493 · DOI:10.1021/tx900367p

MeSH Terms (11)

Animals Cytochrome P-450 CYP3A Glutathione Humans Hydroxylation Macaca fascicularis Microsomes, Liver Oxidation-Reduction Rabbits Swine Thalidomide

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