Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.

Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM, Sportoletti P, Varmeh S, Egia A, Fedele G, Rameh L, Loda M, Pandolfi PP
Sci Signal. 2010 3 (117): ra29

PMID: 20388916 · PMCID: PMC2982149 · DOI:10.1126/scisignal.2000594

MeSH Terms (16)

Animals Cell Cycle Proteins Cell Transformation, Neoplastic DNA-Binding Proteins Humans Introns Male Mice Mice, Transgenic MicroRNAs Minichromosome Maintenance Complex Component 7 Multigene Family Nuclear Proteins Prostatic Neoplasms Proto-Oncogenes PTEN Phosphohydrolase

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