Inhibition of p-STAT3 enhances IFN-alpha efficacy against metastatic melanoma in a murine model.

Kong LY, Gelbard A, Wei J, Reina-Ortiz C, Wang Y, Yang EC, Hailemichael Y, Fokt I, Jayakumar A, Qiao W, Fuller GN, Overwijk WW, Priebe W, Heimberger AB
Clin Cancer Res. 2010 16 (9): 2550-61

PMID: 20388845 · PMCID: PMC2936966 · DOI:10.1158/1078-0432.CCR-10-0279

MeSH Terms (23)

Animals Brain Neoplasms Cell Line, Tumor Cell Proliferation Cell Survival Cyanoacrylates Cytotoxicity, Immunologic Dose-Response Relationship, Drug Drug Synergism Female Immunoblotting Immunologic Factors Interferon-alpha Kaplan-Meier Estimate Killer Cells, Natural Melanoma, Experimental Mice Mice, Inbred C57BL Neoplasm Metastasis Pyridines STAT3 Transcription Factor T-Lymphocytes Treatment Outcome

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