Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

Neale BM, Fagerness J, Reynolds R, Sobrin L, Parker M, Raychaudhuri S, Tan PL, Oh EC, Merriam JE, Souied E, Bernstein PS, Li B, Frederick JM, Zhang K, Brantley MA, Lee AY, Zack DJ, Campochiaro B, Campochiaro P, Ripke S, Smith RT, Barile GR, Katsanis N, Allikmets R, Daly MJ, Seddon JM
Proc Natl Acad Sci U S A. 2010 107 (16): 7395-400

PMID: 20385826 · PMCID: PMC2867697 · DOI:10.1073/pnas.0912019107

MeSH Terms (16)

Alleles Case-Control Studies Cholesterol, HDL Delta-5 Fatty Acid Desaturase Gene Expression Regulation Genome-Wide Association Study Genotype Humans Lipase Lipids Macular Degeneration Oligonucleotide Array Sequence Analysis Polymorphism, Single Nucleotide Reverse Transcriptase Polymerase Chain Reaction Risk Tissue Inhibitor of Metalloproteinase-3

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