Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.

Albaugh VL, Judson JG, She P, Lang CH, Maresca KP, Joyal JL, Lynch CJ
Mol Psychiatry. 2011 16 (5): 569-81

PMID: 20308992 · PMCID: PMC2892549 · DOI:10.1038/mp.2010.33

MeSH Terms (18)

Adipose Tissue Animals Antipsychotic Agents Benzodiazepines Blood Glucose Body Composition Energy Metabolism Glucose Glucose Clamp Technique Lipogenesis Lipolysis Male Motor Activity Olanzapine Rats Rats, Sprague-Dawley Self Administration Time Factors

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