Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis.

Ippagunta SK, Brand DD, Luo J, Boyd KL, Calabrese C, Stienstra R, Van de Veerdonk FL, Netea MG, Joosten LA, Lamkanfi M, Kanneganti TD
J Biol Chem. 2010 285 (16): 12454-62

PMID: 20177071 · PMCID: PMC2852983 · DOI:10.1074/jbc.M109.093252

MeSH Terms (17)

Animals Apoptosis Regulatory Proteins Arthritis, Experimental Autoantibodies CARD Signaling Adaptor Proteins Carrier Proteins Caspase 1 Collagen Cytoskeletal Proteins Dendritic Cells Humans Lymphocyte Activation Mice Mice, Inbred C57BL Mice, Knockout NLR Family, Pyrin Domain-Containing 3 Protein T-Lymphocytes

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