Transmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine.

Field JR, Henry LK, Blakely RD
J Biol Chem. 2010 285 (15): 11270-80

PMID: 20159976 · PMCID: PMC2857005 · DOI:10.1074/jbc.M109.093658

MeSH Terms (15)

Biological Transport Cytoplasm Humans Kinetics Models, Biological Mutagenesis, Site-Directed Mutation N-Methyl-3,4-methylenedioxyamphetamine Protein Binding Protein Conformation Protein Structure, Tertiary Serotonin Serotonin Agents Serotonin Plasma Membrane Transport Proteins Water

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