Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: development of a potent and highly selective M1 PAM.

Bridges TM, Phillip Kennedy J, Noetzel MJ, Breininger ML, Gentry PR, Conn PJ, Lindsley CW
Bioorg Med Chem Lett. 2010 20 (6): 1972-5

PMID: 20156687 · PMCID: PMC2834874 · DOI:10.1016/j.bmcl.2010.01.109

MeSH Terms (5)

Allosteric Regulation Cholinergic Agents Drug Design Receptors, Muscarinic Structure-Activity Relationship

Connections (1)

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