A new dress code for MMPs: cleavage optional.

Fingleton B, Lynch CC
Dev Cell. 2010 18 (1): 3-4

PMID: 20152171 · DOI:10.1016/j.devcel.2010.01.003

Matrix metalloproteinases are well known for their key roles in the processing of extracellular matrix and nonmatrix molecules. Recently, a new theme of proteolysis-independent roles for metalloproteinases has emerged, with a paper from Gonzalo et al. in this issue of Developmental Cell providing an illustration.

(c) 2010 Elsevier Inc. All rights reserved.

MeSH Terms (13)

Animals Bone Remodeling Catalytic Domain Cell Differentiation Cell Fusion Cell Movement Disease Models, Animal Humans Matrix Metalloproteinases Myeloid Cells Osteoclasts Peptide Hydrolases Stem Cells

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