Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway.

Shi J, Guan J, Jiang B, Brenner DA, Del Monte F, Ward JE, Connors LH, Sawyer DB, Semigran MJ, Macgillivray TE, Seldin DC, Falk R, Liao R
Proc Natl Acad Sci U S A. 2010 107 (9): 4188-93

PMID: 20150510 · PMCID: PMC2840082 · DOI:10.1073/pnas.0912263107

MeSH Terms (11)

Amyloid Apoptosis Enzyme Activation Humans Imidazoles Myocardial Contraction Myocardium p38 Mitogen-Activated Protein Kinases Phosphorylation Protein Kinase Inhibitors Pyridines

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