Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure.

Boutaud O, Moore KP, Reeder BJ, Harry D, Howie AJ, Wang S, Carney CK, Masterson TS, Amin T, Wright DW, Wilson MT, Oates JA, Roberts LJ
Proc Natl Acad Sci U S A. 2010 107 (6): 2699-704

PMID: 20133658 · PMCID: PMC2823910 · DOI:10.1073/pnas.0910174107

MeSH Terms (20)

Acetaminophen Animals Arachidonic Acids Catalysis Dose-Response Relationship, Drug Hemeproteins Hemoglobins Humans Hydrogen-Ion Concentration Hydrogen Peroxide Iron Lipid Peroxidation Male Myoglobin Oxidation-Reduction Rats Rats, Sprague-Dawley Renal Insufficiency Rhabdomyolysis Spectrophotometry

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