Phosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice.

Millward CA, Desantis D, Hsieh CW, Heaney JD, Pisano S, Olswang Y, Reshef L, Beidelschies M, Puchowicz M, Croniger CM
J Lipid Res. 2010 51 (6): 1452-63

PMID: 20124556 · PMCID: PMC3035508 · DOI:10.1194/jlr.M005363

MeSH Terms (21)

Adipose Tissue, White Animals Binding Sites Biological Transport Fatty Acids Female Gene Expression Regulation, Enzymologic Glucose Humans Insulin Resistance Lipolysis Liver Male Mice Muscles Phosphoenolpyruvate Carboxykinase (GTP) PPAR gamma Promoter Regions, Genetic RNA, Messenger Sequence Deletion Triglycerides

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