Cataloging the Repertoire of Nature's Blowtorch, P450.

Guengerich FP
Chem Biol. 2009 16 (12): 1215-6

PMID: 20064429 · DOI:10.1016/j.chembiol.2009.12.002

Veith et al. (2009) analyzed over 17,000 compounds for interaction with the five major human cytochrome P450 drug-metabolizing enzymes. Analysis of the results provides some structural insight and framework for expansion.

Copyright 2009 Elsevier Ltd. All rights reserved.

MeSH Terms (8)

Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System Databases, Factual Enzyme Inhibitors Humans Ligands Structure-Activity Relationship Substrate Specificity

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