Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.

Zhuang G, Brantley-Sieders DM, Vaught D, Yu J, Xie L, Wells S, Jackson D, Muraoka-Cook R, Arteaga C, Chen J
Cancer Res. 2010 70 (1): 299-308

PMID: 20028874 · PMCID: PMC3859619 · DOI:10.1158/0008-5472.CAN-09-1845

MeSH Terms (19)

Animals Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Antineoplastic Agents Blotting, Western Breast Neoplasms Cell Line, Tumor Drug Resistance, Neoplasm Female Humans Mice Mice, Nude Receptor, EphA2 Receptor, ErbB-2 Signal Transduction src-Family Kinases Survival Analysis Trastuzumab Xenograft Model Antitumor Assays

Connections (7)

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