A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets.

Su Y, Amiri KI, Horton LW, Yu Y, Ayers GD, Koehler E, Kelley MC, Puzanov I, Richmond A, Sosman JA
Clin Cancer Res. 2010 16 (1): 348-57

PMID: 20028756 · PMCID: PMC3205975 · DOI:10.1158/1078-0432.CCR-09-2087

MeSH Terms (20)

Adult Aged Antineoplastic Combined Chemotherapy Protocols Boronic Acids Bortezomib Chemokines Dacarbazine Drug Administration Schedule Female Humans Male Melanoma Middle Aged NF-kappa B Proteasome Endopeptidase Complex Proteasome Inhibitors Pyrazines Skin Neoplasms Temozolomide Treatment Outcome

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