Human skeletal muscle drug transporters determine local exposure and toxicity of statins.

Knauer MJ, Urquhart BL, Meyer zu Schwabedissen HE, Schwarz UI, Lemke CJ, Leake BF, Kim RB, Tirona RG
Circ Res. 2010 106 (2): 297-306

PMID: 19940267 · DOI:10.1161/CIRCRESAHA.109.203596

MeSH Terms (20)

Atorvastatin Cells, Cultured Cell Survival Fluorobenzenes Gene Expression Profiling HeLa Cells Heptanoic Acids Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Immunoblotting Immunohistochemistry Multidrug Resistance-Associated Proteins Muscle, Skeletal Myoblasts Organic Anion Transporters Pyrimidines Pyrroles Reverse Transcriptase Polymerase Chain Reaction Rosuvastatin Calcium Sulfonamides

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