Conditional mutation of Pkd2 causes cystogenesis and upregulates beta-catenin.

Kim I, Ding T, Fu Y, Li C, Cui L, Li A, Lian P, Liang D, Wang DW, Guo C, Ma J, Zhao P, Coffey RJ, Zhan Q, Wu G
J Am Soc Nephrol. 2009 20 (12): 2556-69

PMID: 19939939 · PMCID: PMC2794231 · DOI:10.1681/ASN.2009030271

MeSH Terms (23)

Animals Apoptosis beta Catenin Cell Line Cell Proliferation Cysts Disease Models, Animal Female Kidney Tubules, Collecting Liver Diseases Male Mice Mice, Congenic Mice, Inbred C57BL Mice, Knockout Mutation Pancreatic Diseases Phenotype Polycystic Kidney, Autosomal Dominant Pregnancy Signal Transduction TRPP Cation Channels Up-Regulation

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