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GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide.

Li L, Rezvan A, Salerno JC, Husain A, Kwon K, Jo H, Harrison DG, Chen W
Circ Res. 2010 106 (2): 328-36

PMID: 19926872 · PMCID: PMC2818799 · DOI:10.1161/CIRCRESAHA.109.210658

MeSH Terms (22)

Animals Binding Sites Biopterin Blotting, Western Carotid Arteries Casein Kinase II Cell Line Cells, Cultured Endothelial Cells Enzyme Inhibitors GTP Cyclohydrolase Humans Intracellular Signaling Peptides and Proteins Mice Mice, Inbred C57BL Mutation NG-Nitroarginine Methyl Ester Nitric Oxide Nitric Oxide Synthase Type III Phosphorylation RNA Interference Stress, Mechanical

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