Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding.

Myers TJ, Brennaman LH, Stevenson M, Higashiyama S, Russell WE, Lee DC, Sunnarborg SW
Mol Biol Cell. 2009 20 (24): 5236-49

PMID: 19846666 · PMCID: PMC2793298 · DOI:10.1091/mbc.e08-12-1256

MeSH Terms (19)

ADAM17 Protein ADAM Proteins Adenosine Triphosphate Animals Calcium CHO Cells Cricetinae Cricetulus ErbB Receptors HL-60 Cells Humans Mice Mitochondria NADPH Oxidases Reactive Oxygen Species Receptors, G-Protein-Coupled Receptors, Purinergic P2 Transcriptional Activation Transforming Growth Factor alpha

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