Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.

Zhang H, Beckman JW, Guengerich FP
J Biol Chem. 2009 284 (50): 35144-53

PMID: 19837980 · PMCID: PMC2787375 · DOI:10.1074/jbc.M109.067397

MeSH Terms (10)

Archaeal Proteins DNA, Archaeal DNA Polymerase beta Frameshift Mutation Humans Hydrogen Bonding Molecular Structure Nucleic Acid Conformation Purines Sulfolobus solfataricus

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