Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.

Kolarovic A, Schweizer E, Greene E, Gironda M, Pallan PS, Egli M, Rozners E
J Am Chem Soc. 2009 131 (41): 14932-7

PMID: 19824732 · PMCID: PMC2823299 · DOI:10.1021/ja904926e

MeSH Terms (13)

Acetals Circular Dichroism Crystallography, X-Ray DNA Models, Molecular Nucleic Acid Conformation Nucleic Acid Denaturation Oligonucleotides Osmotic Pressure RNA RNA Stability Temperature Transition Temperature

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