Homozygosity of the polymorphism MICA5.1 identifies extreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetes.

Triolo TM, Baschal EE, Armstrong TK, Toews CS, Fain PR, Rewers MJ, Yu L, Miao D, Eisenbarth GS, Gottlieb PA, Barker JM
J Clin Endocrinol Metab. 2009 94 (11): 4517-23

PMID: 19820007 · PMCID: PMC2775653 · DOI:10.1210/jc.2009-1308

MeSH Terms (21)

Addison Disease Alleles Autoantibodies Cross-Sectional Studies Diabetes Mellitus, Type 1 Disease Progression Genotype Graves Disease Histocompatibility Antigens Class I HLA-DQ Antigens HLA-DQ beta-Chains HLA-DR Antigens HLA-DRB1 Chains Homozygote Humans Interferon-alpha Microsatellite Repeats Polymerase Chain Reaction Polymorphism, Genetic Risk Factors Steroid 21-Hydroxylase

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