Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probe.

Weaver CD, Sheffler DJ, Lewis LM, Bridges TM, Williams R, Nalywajko NT, Kennedy JP, Mulder MM, Jadhav S, Aldrich LA, Jones CK, Marlo JE, Niswender CM, Mock MM, Zheng F, Conn PJ, Lindsley CW
Curr Top Med Chem. 2009 9 (13): 1217-26

PMID: 19807667 · PMCID: PMC4765323 · DOI:10.2174/156802609789753635

MeSH Terms (6)

Drug Discovery High-Throughput Screening Assays Receptor, Muscarinic M1 Substrate Specificity Sulfonamides Thiadiazoles

Connections (3)

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