Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.

Tolcher AW, Sarantopoulos J, Patnaik A, Papadopoulos K, Lin CC, Rodon J, Murphy B, Roth B, McCaffery I, Gorski KS, Kaiser B, Zhu M, Deng H, Friberg G, Puzanov I
J Clin Oncol. 2009 27 (34): 5800-7

PMID: 19786654 · DOI:10.1200/JCO.2009.23.6745

MeSH Terms (15)

Adult Aged Aged, 80 and over Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Female Humans Infusions, Intravenous Male Maximum Tolerated Dose Middle Aged Neoplasms Neutrophils Receptor, IGF Type 1 Young Adult

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