Identification of genetic variants of human cytochrome P450 2D6 with impaired mitochondrial targeting.

Sangar MC, Anandatheerthavarada HK, Martin MV, Guengerich FP, Avadhani NG
Mol Genet Metab. 2010 99 (1): 90-7

PMID: 19781968 · PMCID: PMC2794965 · DOI:10.1016/j.ymgme.2009.08.009

MeSH Terms (17)

Alternative Splicing Amino Acid Sequence Animals Cytochrome P-450 CYP2D6 Exons Genetic Variation Humans Liver Microsomes Mitochondria, Liver Mitochondrial Proteins Molecular Sequence Data Mutation Protein Sorting Signals Protein Transport Rats Reverse Transcriptase Polymerase Chain Reaction

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