Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents.

Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ
J Clin Invest. 2009 119 (9): 2577-89

PMID: 19726875 · PMCID: PMC2735917 · DOI:10.1172/JCI36714

MeSH Terms (21)

Animals Base Sequence Dietary Fats Gluconeogenesis Hypothalamus Insulin Resistance Isoenzymes Leptin Liver Male Mice Mice, Inbred C57BL Mice, Knockout Palmitic Acid Protein Kinase C Protein Kinase C-theta Rats Rats, Long-Evans RNA, Small Interfering Signal Transduction Subcellular Fractions

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