SOSS1/2: Sensors of single-stranded DNA at a break.

Nam EA, Cortez D
Mol Cell. 2009 35 (3): 258-9

PMID: 19683490 · PMCID: PMC2820400 · DOI:10.1016/j.molcel.2009.07.016

In this issue of Molecular Cell, Huang et al. (2009) describe two heterotrimeric single-stranded DNA binding complexes, SOSS1 and SOSS2, that function downstream of the MRN complex to promote DNA repair and the G2/M checkpoint.

MeSH Terms (9)

Cell Cycle DNA, Single-Stranded DNA-Binding Proteins DNA Breaks, Double-Stranded DNA Repair Genomic Instability Humans Protein Stability Protein Subunits

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