Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth.

Wang H, Lathia JD, Wu Q, Wang J, Li Z, Heddleston JM, Eyler CE, Elderbroom J, Gallagher J, Schuschu J, MacSwords J, Cao Y, McLendon RE, Wang XF, Hjelmeland AB, Rich JN
Stem Cells. 2009 27 (10): 2393-404

PMID: 19658188 · PMCID: PMC2825688 · DOI:10.1002/stem.188

MeSH Terms (21)

Animals Apoptosis Brain Neoplasms Cell Proliferation Cell Survival Cytokine Receptor gp130 Glioma Graft Survival Growth Inhibitors Humans Interleukin-6 Mice Mice, Nude Neoplastic Stem Cells Receptors, Interleukin-6 RNA, Small Interfering RNA Interference Signal Transduction STAT3 Transcription Factor Transplantation, Heterologous Tumor Cells, Cultured

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