Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.

Demetri GD, Chawla SP, von Mehren M, Ritch P, Baker LH, Blay JY, Hande KR, Keohan ML, Samuels BL, Schuetze S, Lebedinsky C, Elsayed YA, Izquierdo MA, Gómez J, Park YC, Le Cesne A
J Clin Oncol. 2009 27 (25): 4188-96

PMID: 19652065 · DOI:10.1200/JCO.2008.21.0088

MeSH Terms (30)

Adult Aged Aged, 80 and over Anthracyclines Antibiotics, Antineoplastic Antineoplastic Agents, Alkylating Australia Dioxoles Disease-Free Survival Drug Administration Schedule Drug Resistance, Neoplasm Europe Female Humans Ifosfamide Infusions, Intravenous Kaplan-Meier Estimate Leiomyosarcoma Liposarcoma Male Middle Aged Neoplasm Staging North America Proportional Hazards Models Risk Assessment Tetrahydroisoquinolines Time Factors Trabectedin Treatment Failure Young Adult

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