Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer.

Qian SB, Waldron L, Choudhary N, Klevit RE, Chazin WJ, Patterson C
J Biol Chem. 2009 284 (39): 26797-802

PMID: 19648119 · PMCID: PMC2785368 · DOI:10.1074/jbc.M109.032334

MeSH Terms (16)

Binding Sites Catalysis Crystallization Crystallography, X-Ray Humans Models, Molecular Mutation Protein Conformation Protein Engineering Protein Multimerization Protein Structure, Tertiary Substrate Specificity Ubiquitin Ubiquitin-Conjugating Enzymes Ubiquitin-Protein Ligases Ubiquitination

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