Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases.

Zhang H, Bren U, Kozekov ID, Rizzo CJ, Stec DF, Guengerich FP
J Mol Biol. 2009 392 (2): 251-69

PMID: 19607842 · PMCID: PMC2755575 · DOI:10.1016/j.jmb.2009.07.019

MeSH Terms (12)

Bacteriophage T7 Base Pair Mismatch Deamination Deoxyribonucleosides DNA DNA-Directed DNA Polymerase DNA Polymerase beta DNA Replication Inosine Kinetics Static Electricity Sulfolobus solfataricus

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