AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.

Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA
Cancer Cell. 2009 16 (1): 21-32

PMID: 19573809 · PMCID: PMC2752826 · DOI:10.1016/j.ccr.2009.04.012

MeSH Terms (16)

Breast Neoplasms Cell Line, Tumor Cell Survival Class I Phosphatidylinositol 3-Kinases Enzyme Activation Female Gene Expression Profiling Humans Mutation Neoplasms Phosphatidylinositol 3-Kinases Protein Serine-Threonine Kinases Proto-Oncogene Proteins c-akt PTEN Phosphohydrolase Pyruvate Dehydrogenase Acetyl-Transferring Kinase Signal Transduction

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