Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study.

Shimada T, Tanaka K, Takenaka S, Foroozesh MK, Murayama N, Yamazaki H, Guengerich FP, Komori M
Chem Res Toxicol. 2009 22 (7): 1325-33

PMID: 19563207 · PMCID: PMC3845904 · DOI:10.1021/tx900127s

MeSH Terms (17)

Aryl Hydrocarbon Hydroxylases Biphenyl Compounds Cytochrome P-450 CYP1B1 Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System Enzyme Inhibitors Flavonoids Humans Hydrocarbons, Aromatic Kinetics Naphthalenes Phenanthrenes Protein Binding Pyrenes Spectrophotometry, Ultraviolet Stilbenes Structure-Activity Relationship

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