Mammalian cytochrome P450 enzymes catalyze the phenol-coupling step in endogenous morphine biosynthesis.

Grobe N, Zhang B, Fisinger U, Kutchan TM, Zenk MH, Guengerich FP
J Biol Chem. 2009 284 (36): 24425-31

PMID: 19561069 · PMCID: PMC2782035 · DOI:10.1074/jbc.M109.011320

MeSH Terms (14)

Animals Benzylisoquinolines Catalysis Cell Line, Tumor Cytochrome P-450 CYP2D6 Cytochrome P-450 CYP3A Humans Iron Mice Morphinans Morphine Oxidation-Reduction Phenols Rats

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