The juxtamembrane region of the EGF receptor functions as an activation domain.

Red Brewer M, Choi SH, Alvarado D, Moravcevic K, Pozzi A, Lemmon MA, Carpenter G
Mol Cell. 2009 34 (6): 641-51

PMID: 19560417 · PMCID: PMC2719887 · DOI:10.1016/j.molcel.2009.04.034

MeSH Terms (19)

Animals Binding Sites Carcinoma, Non-Small-Cell Lung Cell Line Cell Transformation, Neoplastic Chlorocebus aethiops COS Cells Crystallography, X-Ray Dimerization ErbB Receptors Humans Mice Models, Molecular Mutagenesis, Site-Directed Mutation NIH 3T3 Cells Phosphorylation Protein Structure, Tertiary Tyrosine

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